Secondary Malignancies in Retinoblastoma
نویسنده
چکیده
منابع مشابه
Second Malignancies in Retinoblastoma: The Real Problem
Retinoblastoma accounts for 6% of pediatric malignancies under the age of 5 years in the United States, (Broaddus et al., 2008) and epidemiological data suggest that the incidence is standard across populations (Kivelä, 2009). Despite its rarity, observations about the pathogenesis of this disease have enhanced our understanding of genetic cancer syndromes. Germinal or hereditary cases comprise...
متن کاملRetinoblastoma in Southwest Iran
Background: Retinoblastoma is the most common embryonic tumor of retina of children. This tumor include 3-4% of all children malignancies during the age range 0-14 years. In this study, we reported the incidence, therapeutic protocols, and treatment outcome of children with RB in South west Iran. Methods: We retrospectively investigated the medical reports clinical and pathological features of...
متن کاملمروری بر رتینوبلاستوما و گزارش سه مورد رتینوبلاستوم دوطرفه
Retinoblastoma is a retinal malignant tumor that occurs in early childhood. The annual incidence of retinoblastoma is approximately one per 14 000 live births. 250 to 300 new cases are reported in the United States each year. It develops due to inactivation of both alleles of the retinoblastoma susceptibility (RB1) gene. All hereditary cases (55%) are with bilateral and multifocal lesions, but ...
متن کاملSubsequent malignancies and their effect on survival in patients with retinoblastoma.
BACKGROUND As cure rates for retinoblastoma have improved, it is clear that patients with hereditary retinoblastoma experience increased risk of subsequent malignant neoplasms (SMNs). METHODS Using the Surveillance, Epidemiology and End Results (SEER) database, we evaluated risk of SMNs in survivors or retinoblastoma. Standardized mortality ratios (SMRs) were calculated to compare number of d...
متن کاملRadiation induced malignancy in retinoblastoma: new pathology in a case report.
OBJECTIVE Patients with a genetic history of retinoblastoma have an increased risk of developing a second neoplasm. When these secondary malignancies occur in the previously irradiated field of the primary tumor they are most commonly osteosarcomas, fibrosarcomas, and squamous cell carcinomas. We present the first case of a radiation induced adenocarcinoma in a patient after treatment for retin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2010